GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BRCA | cis | rs13191362 | 1 | rs13193282 | chr6:163015442 | PACRG | chr6:163148164-163736523:+ | 0.24 | 4.59 | 5.02E-6 | Body mass index |
| BRCA | cis | rs13196614 | 1 | rs13193931 | chr6:148940808 | UST | chr6:149068271-149398125:+ | 0.35 | 6.32 | 3.93E-10 | Migraine |
| BRCA | cis | rs1577917 | 1 | rs13194429 | chr6:86646705 | SNHG5 | chr6:86386726-86388451:- | -0.59 | -18.56 | 7.27E-67 | Response to antipsychotic treatment |
| BRCA | cis | rs13191362 | 1 | rs13195226 | chr6:163006421 | PACRG | chr6:163148164-163736523:+ | 0.2 | 3.93 | 8.9E-5 | Body mass index |
| BRCA | cis | rs41266839 | 1 | rs13195401 | chr6:26463574 | BTN3A2 | chr6:26365398-26378546:+ | -0.84 | -14.25 | 2.51E-42 | Schizophrenia |
| BRCA | cis | rs41266839 | 1 | rs13195401 | chr6:26463574 | ZNF391 | chr6:27356524-27369227:+ | 0.24 | 3.49 | 0.000497 | Schizophrenia |
| BRCA | cis | rs41266839 | 1 | rs13195402 | chr6:26463575 | BTN3A2 | chr6:26365398-26378546:+ | -0.84 | -14.25 | 2.51E-42 | Schizophrenia |
| BRCA | cis | rs41266839 | 1 | rs13195402 | chr6:26463575 | ZNF391 | chr6:27356524-27369227:+ | 0.24 | 3.49 | 0.000497 | Schizophrenia |
| BRCA | cis | rs13196614 | 1 | rs13196614 | chr6:148923789 | UST | chr6:149068271-149398125:+ | -0.26 | -5.12 | 3.59E-7 | Migraine |
| BRCA | cis | rs1577917 | 1 | rs13196930 | chr6:86652245 | SNHG5 | chr6:86386726-86388451:- | -0.61 | -18.45 | 3.39E-66 | Response to antipsychotic treatment |
| BRCA | cis | rs13196614 | 1 | rs13197062 | chr6:148938030 | UST | chr6:149068271-149398125:+ | 0.35 | 6.36 | 3.04E-10 | Migraine |
| BRCA | cis | rs1577917 | 1 | rs13199006 | chr6:86608708 | SNHG5 | chr6:86386726-86388451:- | -0.58 | -19.32 | 1.53E-71 | Response to antipsychotic treatment |
| BRCA | cis | rs13191362 | 1 | rs13199223 | chr6:163001083 | PACRG | chr6:163148164-163736523:+ | 0.25 | 4.59 | 5.06E-6 | Body mass index |
| BRCA | cis | rs25422 | 1 | rs1319987 | chr6:118782236 | C6orf204 | chr6:118786239-119031238:- | -0.11 | -3.47 | 0.000543 | Renal cell carcinoma |
| BRCA | cis | rs25422 | 1 | rs1319988 | chr6:118782379 | C6orf204 | chr6:118786239-119031238:- | -0.11 | -3.47 | 0.000543 | Renal cell carcinoma |